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Test Description
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D-Xylose Absorption Test

D-xylose is a type of sugar which is normally absorbed by the intestines but it is not used in the body. Eventually the D-xylose is passed out of the body in the urine.

For the D-xylose absorption test, a drink containing the sugar is swallowed. Then the amount of D-xylose in urine and blood samples is measured. The test is done to determine if the intestines are absorbing nutrients properly.

Blood levels of D-xylose are highest about 2 hours after it is swallowed. Almost all of the D-xylose is passed out in the urine within 5 hours. If the intestines cannot absorb the D-xylose properly, its amounts in the blood and urine will be very low.

D-Xylose Absorption Test
Results

Normal

Normal values may vary widely from lab to lab.

D-xylose in blood

Infants to age 5 months:

Greater than 15 milligrams per deciliter (mg/dL) in 1 hour

Children age 6 months to 16 years:

Greater than 20 mg/dL

Adults, age 17 and older:

21–57 mg/dL in 2 hours

D-xylose in urine

Age 65 and younger:

16%–40% of the D-xylose swallowed is found in the 5-hour urine sample

More than 4 grams (g) in a 5-hour urine sample

Age 66 and older:

Greater than 14% of the D-xylose swallowed is found in the 5-hour urine sample

More than 3.5 g in a 5-hour urine sample

More than 5 g in a 24-hour urine sample

Lower than normal values may mean

  • Low amounts of D-xylose in the blood and urine samples suggest that the small intestine is not able to absorb nutrients from food properly. This can be caused by diseases such as Crohn's disease, sprue, celiac disease, and Whipple's disease.
  • Low levels may also indicate inflammation of the lining of the small intestine or an infection with a parasite (such as giardiasis orhookworm disease).
 
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