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Test Description
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Chlamydia Tests

Chlamydia infection is the most common sexually transmitted disease (STD) in the United States. Chlamydia is caused by Chlamydia trachomatis bacteria.

A chlamydia infection may cause a puslike discharge from the penis or vagina, burning during urination, or pelvic pain. However, many chlamydia infections exist with no symptoms.

  • Both in men and women, chlamydia bacteria can infect the eyes, rectum.
  • In women, chlamydia bacteria can infect the fallopian tubes (salpingitis), or several reproductive organs (pelvic inflammatory disease, PID). A chlamydia infection that occurs in a woman's pelvic organs may make her unable to become pregnant (infertile) and can cause other complications if it is not treated in time.
  • In men, chlamydia bacteria can infect the tubes that carry sperm (epididymitis) or produce swelling of the testicles. An untreated infection may make a man unable to father children (infertile).
  • During birth, a newborn can become infected with chlamydia while passing through the mother's infected cervix. Chlamydia in newborns can cause an infection of the eyes and/or lungs. A lung infection may lead to pneumonia.

Several types of tests can help detect a chlamydia infection.

  • Enzyme-linked immunosorbent assay (ELISA, EIA). This common, rapid test detects substances that trigger your immune system to fight the chlamydia infection (chlamydia antigens). EIA testing is done by taking a sample of secretions from the potentially affected area.
  • Direct fluorescent antibody test (DFA). This common, rapid test detects chlamydia antigens. DFA testing is done by taking a sample of secretions from the potentially affected area.
  • Polymerase chain reaction assay (PCR). This test detects the genetic material (DNA) of chlamydia bacteria. PCR testing is very accurate and can be done on either a urine specimen or a sample of secretions from the potentially affected area.
  • Nucleic acid hybridization tests (DNA probe testing). Like the PCR assay, probe testing detects chlamydia DNA. Probe testing is very accurate and can be done by taking a sample of secretions from the potentially affected area. DNA probe testing is more sensitive than chlamydia culture (see below).
  • Chlamydia culture. A culture provides the right environment for chlamydia bacteria to grow. This test is expensive and not commonly done. It requires high technical skills, and obtaining results takes 5 to 7 days. The chlamydia culture test is usually done when the number of bacteria is very low, when child sexual abuse is suspected, or when treatment for infection has failed.

Treatment

Chlamydia can be treated successfully with antibiotic medications, such as tetracycline and erythromycin. For genital infections with Chlamydia trachomatis, all sexual partners of the infected person should also be treated.

Chlamydia Tests
Results

Normal:

Found no chlamydia antigens or DNA. If a culture is performed, no chlamydia bacteria grow in the culture. Additional testing for other STDs may be needed to determine cause of symptoms.

Abnormal:

Chlamydia antigens or DNA are found. If a culture is performed, chlamydia bacteria grow in the culture.

 
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