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Rubella (also called German measles
or 3-day measles) is an illness caused by a virus. Generally, infection causes
no symptoms or a mild illness with a skin rash,
swollen
glands, and a low fever. However, if a woman gets rubella
during her first 3 months of pregnancy, the illness can cause a miscarriage, severe birth defects (such as heart defects,
deafness, cataracts, and mental retardation), or a stillborn baby. The earlier
the infection occurs in a woman's pregnancy, the greater the risks to her antibodies
in the blood that are produced by the immune system to help kill the virus. Once produced,
the antibodies remain in the bloodstream for years. Their presence indicates
that the person has an infection, has been infected in the past, or has been
vaccinated against the disease. A rubella test is usually done for a woman
who is or wants to become pregnant to determine if she has had rubella.
This test is done on a blood sample
taken from a vein.
Rubella Test Results
The results of a rubella test may be given
in titers. A titer is a measure of how much the blood sample can be diluted
before the antibodies against the rubella
virus can not be detected any longer.
A titer of 1 to 8 (1:8) means that
antibodies can be detected when 1 part of the blood sample is diluted by up
to 8 parts of a salt solution (saline). A larger second number means there
are more antibodies in the blood. Therefore, a titer of 1 to 32 indicates
more rubella antibodies in the blood than a titer of 1 to 8.
A titer higher than 1 to 10 (such
as 1:16 or 1:32) usually indicates that a woman is protected against rubella.
An initial rubella test may be done
when a person first has symptoms of rubella (such as a mild rash, swollen
glands, and a slight fever). A second rubella test may then be done when the
person recovers. If titer levels in the second sample are four or more times
greater than the first sample, a diagnosis of a recent rubella infection is
confirmed.
A titer of 1 to 8 (1:8) in an infant 6 months or older indicates that he or
she was infected with the rubella virus during the mother's pregnancy (congenital
rubella).