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Nutritional Supplements
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The Modern Diet and Nutrition

 

  Jeffrey Bland, Ph.D., a biochemist and nutrition expert from Gig Harbor, Washington, says, the leading nutritional problem in the United States today is "overconsumptive undernutrition," or the eating of too many of these empty-calorie foods. Although people in the United States consume plenty of food, it is not the right kind of food. Statistically, studies have concluded that almost two-thirds of an average American's diet is made up of fats and refined sugars having low to no nutrient density. This contributes to nutrient deficiencies that can rob the body of its natural resistance to disease and premature aging, while weakening its overall physiological and psychological performance. Consequently, the remaining one-third of the average diet is counted on for the essential nutrients needed to keep up health, which may or may not be from high-nutrient-density food.

  The United States Department of Agriculture (USDA) has found that a significant percentage of the United States population receives well under 70 percent of the U.S. Recommended Daily Allowance (U.S. RDA) for vitamin A, vitamin C, B-complex vitamins, and the essential minerals calcium, magnesium, and iron. A separate study found that most typical diets contained less than 80 percent of the RDA for calcium, magnesium, iron, zinc, copper, and manganese, and that the people most at risk were young children and women, adolescent to elderly. The chart on pages 389-392 indicates the adult RDA requirements for vitamins and minerals, as well as adult maintenance and therapeutic ranges recommended by many nutritional experts.

  The standard American diet has been continually cited by numerous studies conducted since the 1960s as a contributing, causative factor in a variety of "killer" diseases, including coronary heart disease, atherosclerosis, strokes, high blood pressure, diabetes, arthritis, and colitis. According to Dr. Berkson, there may also be increased risk of female disorders associated with diets high in processed fats (trans-fatty acids) and increased consumption of refined sugar and caffeine.

  

Recommended Daily Allowances

 

  A group of government-sponsored scientists in the United States developed the generally accepted reference standard for nutritional adequacy - the U.S. Recommended Daily Allowance (U.S. RDA). Its function is to provide levels of essential nutrients that prevent classic deficiency diseases, and set marginal daily guidelines for average population groups. As it was difficult for the scientists to agree upon the RDA's, they built within the guidelines instructions to keep reviewing and changing the RDA's every four years as new information is discovered. Today, in the wake of overwhelming clinical evidence that shows a wide variance in each person's individual nutritional needs, a growing number of scientists have begun to dispute the validity of RDA standards.

  While a diet adequate in RDA's may be appropriate to avoid severe nutritional deficiency diseases such as rickets, scurvy, or beriberi, it may not be appropriate to avoid more mild deficiency reactions such as nervousness, insomnia, mental exhaustion, improper immune function, or proneness to injury.

  Emmanuel Cheraskin M.D., D.M.D., suggests that IDA's - Ideal Daily Allowances - should replace RDA's, to make up for the limiting nature inherent in the current method. In line with the growing body of research regarding nutrients, the FDA (Food and Drug Administration) in 1994 will introduce a new nutritional label reference known as the Reference Daily Intake (RDI), to ensure that food labeling be more consistent with the latest data on nutrient allowances.

Symptoms of Nutritional Deficiency

 

  Historically, doctors and nutritional scientists only recognized nutritional deficiencies if they actually manifested as diseases such as beriberi, pellagra, or rickets. If a patient had no overt symptoms or disease, he or she was regarded as healthy and adequately nourished. According to Dr. Berkson, today, doctors and scientists are beginning to recognize mild and moderate nutritional deficiencies, the symptoms of which may often be subtle, overlapping, and varied. Many times these symptoms are taken for granted as being part of the aging process. Nutritional doctors and scientists are learning, however, that these symptoms are actually subtle deficiency signs that can be responsive to nutrient supplementation and dietary improvement. Greater understanding and better testing methods are leading to the diagnosis of more and more subtle nutrient imbalances.

  For example, the first signs of B vitamin deficiency may include subtle changes in behavior: insomnia, mood swings, and an inability to concentrate. Myron Brin, Ph.D., says, these early warning signs demonstrate that social function may be adversely affected by chronic vitamin deficiency.

  Other symptoms of nutritional deficiencies can include fatigue, nervousness, mental exhaustion, confusion, anemia, and muscle weakness. It has been reported that marginal deficiencies of vitamins A, C, E, and B6 may also reduce immunocompetence, impairing the body's ability to ward off disease and repair tissues.

 

Biochemical Individuality

 

  Scientists have increasingly begun to examine whether the standardized U.S. RDA guidelines are sufficient for individual nutritional needs. Roger Williams, Ph.D., a pioneering biochemist, discovered vitamin B5 (pantothenic acid) in the 1930s. In his book, Nutrition Against Disease, Dr. Williams expresses his belief that each person is genetically unique, and therefore requires slight variations in nutrient intake to function optimally. He calls this principle biochemical individuality. Dr. Williams also believes that all living creatures are greatly affected by the overall quality, balance, and quantity of food ingested.

  The concept of biochemical individuality has brought about many changes, including the emergence of new preventive diagnostic procedures, such as nutrition assessment and risk factor analysis. These utilize physiological data, personal and family health history, dietary intake analysis, and scientifically advanced biochemical screenings to help nutritional practitioners determine individual biochemistry and nutritional status.

Essential Nutrients

 

  Dr. Bland says that essential nutrients are those nutrients derived from food that the body is unable to manufacture on its own. These are absolutely necessary for human life and include eight amino acids, at least thirteen vitamins, and at least fifteen minerals, plus certain fatty acids, water, and carbohydrates.

  Amino acids are the building blocks of protein. The essential amino acids are L-isoleucine, L-leucine, L-valine, L-methionine, L-threonine, L-phenylalanine, and L-tryptophan.

  Essential vitamins are broken up in two groups: fat-soluble and water-soluble. The essential vitamins classified as fat-soluble include vitamin A, vitamin D, vitamin E and vitamin K. The water-soluble essential vitamins are vitamin C (ascorbic acid), vitamin B1 (thiamine), vitamin B2 (riboflavin), vitamin B3 (niacin), vitamin B5 (pantothenic acid), vitamin B6 (pyridoxine), vitamin B12, folic acid, and biotin.

  The essential minerals include calcium, magnesium, phosphorus, iron, zinc, copper, manganese, iodine, chromium, potassium, sodium, and a number of trace elements. They make up part of the necessary elements of body tissues, fluids, and other nutrients and play an active role in the body's regulatory functions. Low levels of these nutrients have been linked to such conditions as heart disease, high blood pressure, cancer, osteoporosis, depression, schizophrenia, and problems relating to menopause.

  Essential fatty acids required for proper metabolism include linoleic and linolenic acid, found in seafood and unrefined vegetable oils, plus oleic and arachidonic acids, found in most organic fats and oils and peanuts. These also play an important role in reducing heart disease and in the treating of conditions such as eczema and premenstrual stress.

Accessory Nutrients

 

  There are also many nonessential nutrients, called accessory nutrients or co-factors, that work in harmony with the essential nutrients to aid in the breakdown and conversion of food into cellular energy, and also help support all of the body's physical and mental functions.

   Some of the accessory nutrients that help support metabolism include vitamin B-complex co-factors choline and inositol, as well as coenzyme Q10 (a close relative of the B-vitamins), and lipoic acid, according to Dr. Bland,

  Other accessory nutrients which have demonstrated preventative functions include B-complex co-factor PABA (para-aminobenzoic acid), and substance P or bioflavonoids which work with vitamin C. Certain amino acids found in protein are also considered nonessential because they can be synthesized by the body from the essential amino acids.

 

Vitamin and Mineral Supplement Ranges

 

U.S. RDA Adult

Adult Daily Supplement Range

FAT-SOLUBLE VITAMINS

Beta-carotene pro-vitamin A: Converted by the body to vitamin A as needed. Primary antioxidant which helps protect the lungs and other tissues.

Not established

10,000 - 50,000 IU

Possible side effects: Prolonged ingestion of relatively high doses may cause a nonharmful yellowing of the skin, especially palms and soles. Avoid beta-carotene supplement while taking the prescription drug Accutane, especially during pregnancy.

Vitamin A (preformed retinol): Essential for growth and development, maintenance of healthy skin, hair, and eyes. Involved in wound healing.

4000 - 5000 IU

5,000 - 10,000 IU

Possible side effects: Prolonged ingestion of excess vitamin A (50,000 IU+/day) may be toxic. Avoid vitamin A supplement while taking the prescription drug Accutane, especially during pregnancy.

Vitamin D cholecalferol: Essential for calcium and phosphorus metabolism, required for strong bones and teeth.

400 IU

200-400 IU

Possible side effects: Prolonged ingestion of excess vitamin D (1,000 IU+/day) may be toxic and cause hypercalcemia (excess of calcium in blood).

Vitamin E (alpha tocopherol): Primary antioxidant which protects red blood cells and is essential in cellular respiration.

12 -15 IU

200 - 800 IU

Possible side effects: Prolonged ingestion of vitamin E may produce adverse skin reactions and upset stomach.

Vitamin K (phylloquinone): Integrally involved in the blood clotting mechanism.

65 mcg.

50-500 mcg.

Possible side effects: Unlike the other fat-soluble vitamins, vitamin K is not stored in significant quantity in the liver. Synthetic vitamin K (menadione) is toxic in excess dosages.

WATER-SOLUBLE VITAMINS

Vitamin C (ascorbic acid): Primary antioxidant, essential for tissue growth, wound healing, absorption of calcium and iron and utilization of the B vitamin folic acid. Involved in neurotransmitter biosynthesis, cholesterol regulation, and formation of collagen.

 

60 mg.

300-3,000 mg.

Possible side effects: Essentially nontoxic in oral doses. However, excessive ingestion may cause abdominal bloating, gas, flatulence, and diarrhea. Acid-sensitive individuals should take buffered ascorbate form of vitamin C supplement.

Vitamin B1(thiamine): Essential for food metabolism and release of energy for cellular function.

1.2-1.5 mg.

5-100 mg.

Possible side effects: Essentially nontoxic in oral doses.

Vitamin B2 (riboflavin): Essential for food metabolism and release of energy for cellular function. Important in the formation of red blood cells and activation of other B vitamins.

1.4-1.8 mg.

5-100 mg.

Possible side effects: Essentially nontoxic in oral doses. Moderate to high doses of vitamin B2 may cause nonharmful bright yellow coloration of urine.

Vitamin B3 (niacin): Essential for food metabolism and release of energy for cellular function. Vital for oxygen transport in the blood, and fatty acid and nucleic acid formation. A major constituent of several important coenzymes.

16-20 mg.

20-100 mg.

Possible side effects: Essentially nontoxic in normal oral doses. High doses (100 mg+) may cause transient flushing and tingling in the upper body area, as well as stomach upset. Prolonged ingestion of excess vitamin B3 (1,000 mg-2,000 mg+/day) may elevate liver enzymes and cause liver damage.

Vitamin B5 (pantothenic acid): Involved in food metabolism and release of energy for cellular function. Vital for biosynthesis of hormones and support of the adrenal glands.

4-7 mg.

10-1,000 mg.

Possible side effects: Essentially nontoxic in oral doses. Extremely high doses (10,000 mg+) will produce diarrhea.

Vitamin B6(pyroxidine): Involved in food metabolism and release of energy. Essential for amino acid metabolism, and formation of blood proteins and antibodies. Helps regulate electrolytic balance.

2.0-2.5 mg.

5-200 mg.

Possible side effects: Prolonged high doses (500 mg+/day) may be toxic and cause neurological damage. Prescription oral contraceptives may cause deficiency of vitamin B6.

 

Vitamin B12 (cobalamin): Essential for normal formation of red blood cells. Involved in food metabolism, release of energy and maintenance of epithelial cells (cells that form the skin's outer layer and the surface layer of mucous membranes) and the nervous system.

3.0-4.0 mcg.

10-500 mcg.

Possible side effects: Essentially nontoxic in oral doses.

Folate (folic acid, folacin): Essential for blood formation, especially red blood cells and white blood cells. Involved in the biosynthesis of nucleic acids including RNA/DNA.

400 mcg.

200-800 mcg.

Possible side effects: Essentially nontoxic in oral doses. An excess intake of folate can mask a vitamin B12 deficiency.

Biotin: Essential for food metabolism and release of energy. Assists in the biosynthesis of amino acids, nucleic acid, and fatty acids. Utilization of other B vitamins.

150-300 mcg.

300-600 mcg.

Possible side effects: Essentially nontoxic in oral doses.

B vitamins should also be taken in a B-complex form because of their close interrelationship in metabolic processes.

MINERALS

The functions of minerals are highly interrelated to each other and to vitamins, hormones, and enzymes. No mineral can function in the body without affecting others.

Calcium (Ca++): Essential for strong bones and teeth. Serves as a vital cofactor in cellular energy production, and nerve and heart function.

800-1,200 mg.

200-1,200 mg.

Possible side effects: Prolonged ingestion of excess calcium, along with excess vitamin D may cause hypercalcemia of bone and soft tissue (such as joints and kidneys) and may also cause a mineral imbalance.

Magnesium (Mg++): Essential catalyst for food metabolism and release of energy. A cofactor in the formation of RNA/DNA, enzyme activation, and nerve function.

300-350 mg.

150-600 mg.

Possible side effects: Extremely high doses (30,000 mg+) may be toxic in certain individuals with kidney problems. Doses of 400 mg+ may produce a laxative effect, causing diarrhea.

Potassium (K+): A primary electrolyte, important in regulating pH (acid/base) balance and water balance. Plays a role in nerve function and cellular integrity.

Not established

1,875-5,625 mg.*

*(A typical healthy diet contains adequate potassium. Very active individuals may require additional electrolytes).

Possible side effects: Extremely high doses (25,000 mg+/day) of K chloride may be toxic in instances of kidney failure.

Sodium (Na+): A primary electrolyte, important in regulating pH (acid/base) balance and water balance. Plays a role in nerve function and cellular integrity.

Not established

Limit your daily intake to 1,500 mg.

Possible side effects: Prolonged ingestion of excess sodium has been linked to high blood pressure and increased incidence of migraine headaches. Extremely high intakes of sodium can result in swelling of tissues called edema.

Phosphorus (P): Constituent of the molecule phosphate, which plays a major role in energy production and activation of B vitamins. Component of RNA/DNA, bones, and teeth.

900-1,200 mg.

300-600 mg.

Possible side effects: Although essentially nontoxic, a disproportionately large amount of phosphorus relative to calcium intake may cause a deficiency in calcium and mineral imbalance.

Zinc (Zn++): Cofactor in numerous enzymatic processes and reactions. Structural constituent of nucleic acids and insulin. Involved in taste, wound healing, and digestion.

15 mg.

15-30 mg.

Possible side effects: Extremely high doses (2,000 mg+/day) can be toxic. Excess zinc intake (50 mg+/day) may cause copper deficiency and mineral imbalance.

Iron (FE++ or FE+++): Combines with other nutrients to produce vital blood proteins. Involved in food metabolism.

10-18 mg.

10-30 mg.

Possible side effects: Prolonged ingestion of excess iron can be toxic, affecting the liver, pancreas, heart, and nucleus and increasing susceptibility to infection. Poorly utilized forms of iron (Fe sulfate or Fe gluconate) may cause constipation and/or stomach upset. Iron supplements should be taken with food and supplemental vitamin C.

Manganese (Mn++): Important catalyst and cofactor in many enzymatic processes and reactions. Helps maintain skeletal and connective structural tissue, as well as cellular integrity.

2.5-5.0 mg.

2-10 mg.

Possible side effects: Prolonged ingestion of excess manganese may result in nonharmful elevated concentrations in the liver and may cause a mineral imbalance.

Copper (Cu++): Essential for production of red blood cells. Involved in the maintenance of skeletal and cardiovascular systems. Works with vitamin C in the biosynthesis of collagen and elastin.

2-3 mg.

2-3 mg.

Possible side effects; Prolonged ingestion of excess copper may be toxic, especially with Wilson's disease, a rare metabolic disorder resulting in an excess accumulation of copper in the liver, red blood cells, and the brain.

Iodine (I-): Essential component of thyroid hormones which regulate growth and rate of metabolism.

150 mcg.

50-300 mcg.

Possible side effects: Prolonged ingestion of excess iodine may cause "iodine goiter," an enlargement of the thyroid gland. May also induce acne-like skin lesions or aggravate preexisting acne conditions.

Chromium (Cr+++): Vital as cofactor of GTF (glucose tolerance factor), which regulates the function of insulin. Involved in food metabolism, enzyme activation, and regulation of cholesterol.

50-200 mcg.

200-500 mcg.

Possible side effects: Essentially nontoxic in oral doses.

Selenium (Se): Important constituent of the antioxident enzyme gluathione peroxidase which is contained in white blood cells and blood platelets. Synergistic nutritional partner of vitamin E.

55-200 mcg.

100-200 mcg.

Possible side effects: Prolonged ingestion of excess selenium may be toxic.

 

 

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